| Billy West | Fry, Prof. Hubert Farnsworth, Zoidberg, Zapp Brannigan |
| Katey Sagal | Taronga Leela |
| John DiMaggio | Bender Unit 22, Elzar the Chef |
| Tress MacNeille | Mom, Suicide Booth, Robot daughters |
| Dave Herman | Florp the Comedian, Mayor Poopenmeyer, Dean Vernon, Wernstrom |
| Maurice LaMarche | Calculon, Kif, Murg the High Priest |
| Phil LaMarr | Hermes Conrad |
| Lauren Tom | Amy Wong |